On November 13 - 15 2016, Sulev Kõks from UT/EMU participated in the conference “Developing interventions for frailty” in Vienna, Austria. This conference focused on the biomarker discovery and study design problems related to the age-related diseases. Biomarker discovery requires analysis of complex biological data and machine learning. One topic was cellular senescence and regenerative decline that is fundamental for ageing and degenerative disorders. There was session about neurodegenerative disorders (Parkinson’s disease, Alzheimer’s disease). Another lecture focused on the gene and cell therapies that provide stem cell based intervention for the frailty and age-related regenerative problems. Also, the possibilities of computational physiology to enable personalised medicine were discussed. Sulev Kõks learned the biomarker study design, cell therapy and systems biology. He also participated in the round table discussions and presented the activities of Searmet project.