Events

Contact

Estonian University of Life Sciences

Institute of Veterinary Medicine and Animal Sciences

www.emu.ee

Prof. Ülle Jaakma

Principal Investigator

Ylle.Jaakma@emu.ee

Hector Pagan

Project manager

hector@ut.ee

+372 7313 706

Seminar "Technology Transfer and patenting. Experiences and practices of Copenhagen University."

 

On 19th of September 2017 a seminar "Technology Transfer and patenting. Experiences and practices of Copenhagen University" took place in EMU Assembly Hall. Seminar was organized by Estonian University of Life Sciences in cooperation with the University of Copenhagen. Niels Lysholm Engelhard from UCPH Tech Trans Office conduced a seminar where following topics were discussed: 

·        Introduction to technology transfer (history, what is in it for the researchers, and other stakeholders?)

·        Intellectual property rights with special focus on patent rights

·        Patent strategy

·        What is a patent?

·        The route from a patent application to a granted patent

·        The use of patent literature as a resource for the researchers

·        How to carry an assessment of an invention?

·        The commercialization process

·        How to identify potential commercial partners?

·        Different strategies to maximize the value from IP

·        Licensing strategies and negotiation of license agreements.

The sessions included different tools and practical examples from the University of Copenhagen.

Seminar was organized in the framework of H2020 SEARMET project. 

 

SEARMET Steering Committee in Tartu on September 7th 2017

 

 

At the beginning of September, SEARMET project team met again in Tartu, Estonia. During the Steering Committee meeting different upcoming deliverables, trainings as well as the organization of Searmet Winter School „Molecular Biology in Animal Sciences“ was discussed by the partners. Project team decided to have our next SEARMET Steering Committee meeting in March 2018 in UK. 

 

 

Two workshops organized by EMU and University of Sheffield in September 2017

Estonian University of Life Sciences in cooperation with the University of Sheffield organized two workshops on September 7th and 8th 2017. Both of the workshops were conducted by professor William Holt (more information about Prof. Holt may be found here) and Mrs. Lisa Thurston (more information about Mrs. Thurston may be found here) from the University of Sheffield.

The first „Presentation Skills Workshop“ took place on September 7th in the building of the Institute of Veterinary Medicine and Animal Sciences, EMU (Kreutzwaldi 62, room B-119). The target audience of this workshop was mainly students and very early career scientists. The workshop was divided into two parts:

  1. Informal presentation and discussion including:

„How to successfully prepare and present your periconception research“

„How teaching periconception at the undergraduate level differs from presenting your data to scientific colleagues“

  1. Student Presentations and Constructive Feedback

The second workshop on topic „Scientific Writing Workshop and Drop-in Writing Clinic“ took place on September 8th at 09:00 – 12:00 in the building of the Institute of Veterinary Medicine and Animal Sciences, EMU (Kreutzwaldi 62, room B-119). The target audience of this workshop was students, very early career scientists and any staff member struggling to write scientific articles for English-speaking journals. The workshop was divided into two parts:

  1. Informal presentation and discussion regarding, ‘How to write a scientific review’

  2. Scientific writing drop-in session

Both of the workshops were conducted in the frames of Horizon 2020 project SEARMET.

More information: Hemminki Otstavel, SEARMET project assistant, +372 56 354 033

hemminki.otstavel@ut.ee%20" target="_blank">hemminki.otstavel@ut.ee or hemminki.otstavel@emu.ee.

Workshop "Curriculum Deveopment" on 5th of September 13:30 - 16:30

On 5th of September 2017 the workshop „Curriculum Development“ took place at EMU main building (Kreutzwaldi 1, room 104). Workshop was organized by EMU in cooperation with the University of Sheffield. The workshop was conducted by Professor Michelle Marshall from the University of Sheffield. She is a Director of Learning and Teaching in the Academic Unit of Medical Education of the Medical School in the University of Sheffield. More information about Prof. Marshall may be found here

The content of the training was mostly about the pedagogy/theory of learning and teaching as well as practical approaches to developing and delivering teaching and educational activities. The topics that were included in the training: engaging with stakeholders, setting aims and objectives, course design, approaches to teaching, assessment and evaluation. There were also discussed following themes:

*   Different teaching and learning approaches  - how to find a good balance?

*   Is there any space for e-learning in medical curriculum?

*   Student engagement – how to motivate students for the independent learning and improvement of practical skills?

*   Feedback  in curriculum development

*   Transferable skills – should we address them in the medical/veterinary curriculum?

The training was conducted in the frames of Horizon 2020 project SEARMET.

Slides from the meeting as well as video record of the lecture will be available soon. 

If you have any questions, please contact SEARMET project assistant Hemminki Otstavel (emminki.otstavel@ut.ee/hemminki.otstavel@emu.ee">hemminki.otstavel@ut.ee/hemminki.otstavel@emu.ee, +372 56354033​)

 

SEARMET Workshop "Managing Research Projects" by project manager Hector Pagan on August 25th 2017

On 25th of August 2017, SEARMET project manager Hector Pagan conducted a workhop on topic „Managing Research Projects“ at EMU.

The main goal of the workshop was to teach PhD students and postdocs about managing their research projects and discuss the most common mistakes. Hector introduced the three elements that most funders look for when supporting projects: excellence, implementation and impact. He discussed more in deep what funders look for in each - with a focus on impact and implementation. He also shared his experiences and explained his approach to writing proposals.

As Hector Pagas has several experience in writing research proposals for different funders as well as managing different EU funded projects, PhD students were able to receive individual consultation after the workshop and receive feedback to their research proposals. In case you would like to get the slides of the meeting, please contact SEARMET project assistant Hemminki Otstavel (hemminki.otstavel@ut.ee or hemminki.otstavel@emu.ee +37256354033)

 

 

International Summer School of H2020-TWINN-2015 WIDENLIFE project (Grant No 692065) and SEARMET project (Grant No 692299)

We are happy to announce that the two H2020-TWINN-2015 projects WIDENLIFE (Grant No 692065) and SEARMET (Grant No 692299) are organizing an International Summer School on topic "Single-cell and low-input methodologies in reproductive biology". It will take place in Tartu, Estonia from June 13-14th 2017.

Venue: Institute of Molecular and Cell Biology, University of Tartu, Omicum building, Riia 23b/2, auditorium 105.

More information about the Summer School and registration available at: https://sisu.ut.ee/widenlife . The registration is open until the 5th of June 2017.

 

PROGRAMME:

Tuesday, June 13, 2017

10:30-11:00 Welcome coffee
11:00 Opening words, Professor Ants Kurg, University of Tartu and Professor Ülle Jaakma, Estonian University of Life Sciences


I session:
11:10-11:55 Ann Van Soom, PhD, Ghent University, Belgium “Emerging role of extracellular vesicles in communication of preimplantation embryos in vitro
11:55-12:40 Martin Anger, PhD, CEITEC, Czech Republic “Challenges of chromosome segregation in oocytes and early embryos in mammals
12:40-14:00 Lunch break (lunch with invitations)


II session:
14:00-14:45 Jennifer Southcombe, PhD, and Ingrid Granne, PhD, University of Oxford, United Kingdom “Paternal and maternal immunological factors in the peri-implantation endometrium14:45-15:30 Mariann Koel, MSc, University of Tartu, Estonia “The interactome of human embryo implantation
15:30-16:00 Coffee break III session: 16:00-16:45 Nathalie Brison, PhD, University of Leuven, Belgium „Non-invasive prenatal testing: clinical and biological challenges
16:45-17:30 Eftychia Dimitriadou, PhD, University of Leuven, Belgium “Genome-wide approaches for preimplantation genetic diagnosis and screening

Wednesday, June 14, 2017

09:30-10:00 Welcome coffee


IV session:

10:00-10:45 Joris Vermeesch, PhD, University of Leuven, Belgium “The embryo is the cradle of chromosomal disorders, chimaerism and mixoploidy
10:45-11:30 Olga Tšuiko, MSc, University of Tartu, Estonia “Unravelling chromosomal instability in mammalian preimplantation embryos"
11:30-12:15 Ene Reimann, PhD, University of Tartu, and Monika Nõmm, Estonian University of Life Sciences, Estonia “Bovine embryo genomics using NGS
12:15-14:00 Lunch break (lunch with invitations)


V session:
14:00-14:45 Jan Ole Bertelsen Secher, PhD, University of Copenhagen, Denmark “In vivo testing of porcine iPSC
14:45-15:30 Björn Heindryckx, PhD, Ghent University Hospital, Ghent University, Belgium “In vitro generated gametes from stem cells: to be or not to be
15:30-16:00 Coffee break
16:00-16:45 Mait Metspalu, PhD, Estonian Biocentre, Estonia “Reconstructing population histories from genetic diversity patterns
Closing remarks

 

Funded by the European Union through the Coordination and Support Action of the H2020 programme under grant agreement No 692065 „Widening the Scientific Excellence for Studies on Women’s and Fetal Health and Wellbeing“, No 692299 "Scientific Excellence in Animal Reproductive Medicine and Embryo Technology" and European Regional Development Fund through University of Tartu ASTRA project PER ASPERA

 

For further information, please contact Hemminki Otstavel (hemminki.otstavel@ut.ee; +37256354033) 

Maamess on 20th to 22nd of April 2017

 

On April 20-22, the 25th international agricultural fair Maamess took place in Tartu, Estonia. The fair brought together more than 45 000 visitors, 460 companies from 10 countries, and covered over 60 000 m2 of exhibition space. This year, Maamess focused on four main topics: agriculture, forestry, gardening and food.

 

Representatives from the EMU also participated in the fair and introduced the SEARMET project. Information about the ovum pick up and in vitro production of bovine embryos was presented to the visitors and other highlights concerning the topics relevant for the project were shared. 

 

AgroForum Mare Balticum 2017 - Agriculture for Rural Development

 

AgroForum Mare Balticum 2017, taking place on April 18-20, was already 5th such event in succession. This year’s focus was “Agriculture for Rural Development”. Four general themes were covered during the event: agriculture as one of the basis for rural development; agricultural subsidies and support measures; animal husbandry in rural development and rural environment protection; risk management in rural sector. One of the SEARMET project partners, Estonian University of Life Sciences, is one of the main organizers of the forum.

The AgroForum was targeted at decision makers on political, administrative, research and producers’ associations level, i.e. ministers of agriculture and other higher state public servants, representatives of agricultural universities, food processors and producers’ associations.

The AgroForum involved the countries bordering the Baltic Sea, such as Finland, Sweden, Denmark, Germany, Poland, Lithuania, Latvia and Russia, and also the Eastern partnership countries, such as Ukraine, Moldova, Armenia, Azerbaijan, Belarus and Georgia.

 

International seminar „Open Research Data - the FAIRest Data is the Future of Science“

 

In cooperation of the University of Tartu Library and DataCite Estonia Consortium an international seminar "Open Research Data - the FAIRest Data is the Future of Science" was held. The seminar took place on 20th of April in Tallinn University of Technology. The target group of the seminar was researchers, doctoral students, data managers and research administrative staff who are supposed to preserve and open up their research data. This seminar examined state-of-the-art institutional repositories and common problems, provided networking opportunities and sharing of best practices.

Third presentation of a new series of scientific seminars on 20th of April

 

The third presentation of a new series of scientific seminars took place on 20th of April 2017. James Ord, a PhD student from Prof. Alireza Fazeli's laboratory from the University of Sheffield gave his presentation on the topic "Sins of the Father: Transgenerational Effects of Environmental Stress in Fish". More information about his background and research may be found: http://fazelilab.group.shef.ac.uk/Ord.html

The presentation slides are available here: slides

 

Workshops in MASTERRIND on 20th to 24th of February 2017

 

Headquarters of MASTERRIND embryo station with Knut Roschlau

 

Farm for oocyte and embryo donors, Nückel

 

Schau der Besten, 2017, Verden

 

In February Elina Mark, Jevgeni Kurõkin, Andres Reilent and Ants Kavak from the EMU went to Germany. The objective of the trip was to visit the MASTERRIND ET-station and embryo laboratories in Verden, and the OPU station in Nückel.

 

Elina, Jevgeni, Andres and Ants participated in several workshops – in embryo lab: in vitro production of bovine embryos, freezing of embryos, preparations for embryo transfers;  in OPU-station: Ovum Pick-Up techniques, donor preparation;  in ET-station: flushing of embryos from donors, recipient preparation for embryo tranfer. They also  visited one of the biggest cattle shows in Europe: Schau der Besten 2017, and went to AI and bull station in Verden.

 

During the visit and workshops EMU veterinarians gained new ideas about Ovum Pick-Up techniques: donor preparation – hormonal stimulation vs no stimulation; aparature used for oocyte aspiration and handling; embryo flushing techniques; recipient preparation – correct monitoring of the time of heat, optimal time for embryo transfer. In the embryolab they had an opportunity to learn how to take embryo biopsy with micromanipulator and how to perform embryo sexing and genetic analysis; additionally an overview of in vitro maturation, fertilization and culture techniques of bovine embryos, and of embryo slow-freezing method were given.

 

For the future use in our laboratory in EMU the visitors got MASTERRINDs media composition formulas for IVM, IVF and IVC.

Second presentation of a new series of scientific seminars on 3rd of February 2017

 

The second presentation of a new series of scientific seminars took place on 3rd of February 2017 in the seminar room on the second floor of the UT's Translational Medicine Centre (Ravila 14b, Tartu). 

 

The presentation was given by Olga Tšuiko, who is a PhD student from the Department of Obstetrics and Gynecology (UT). The title of her presentation was: "Unraveling chromosomal instability in early cleavage stage embryos using bovine as a model".

 

For additional information please contact: Hemminki Otstavel (hemminki.otstavel@ut.ee), +37256354033

 

The presentation slides are available here: slides

 

SEARMET PhD students' seminar with prof. Alireza Fazeli and prof. William Holt

 

Last seminar in the series of PhD students' seminars took place on 2nd of February 2017. This time we had professor William Holt from the University of Sheffield visiting us. His main research has focused on the methods for the assessment and preservation of gametes, especially spermatozoa, in a variety of species. More information about prof. William Holt can be found here: http://fazelilab.group.shef.ac.uk/Holt.html

 

The agenda of the seminar was following:

Time

Name

University

Topic

09:00-09:05

Alireza Fazeli

USFD

Introduction

09:05-09:40

Marilin Ivask

UT

"High-fat diet influence on Wfs1 heterozygous mice"

09:40-10:15

Freddy Lättekivi

UT

"Offspring of long-snouted seahorses on different diets: de novo transcriptome assembly and analysis of differentially expressed genes"

10:15-10:50

Ulrika Tuppits

EMU

"Local inflammatory response in mares’s uterus before and after insemination with frozen-thawed semen"

10:50-11:25

Aili Tagoma

UT/EMU

„The effect of extracellular vesicles in fetal bovine serum on Jar sphere outgrowth“

11:25-11:40

Small break

 

 

11:40-12:15

Rutt Taba

UT

"RNA sequencing of bovine blastocysts"

12:15-12:50

Lidiia Zhytnik

UT

"Genetic predisposition to Osteogenesis Imperfecta"

12:50-13:25

Hanneloore Kiiver

EMU

„The effects of milk progesterone and activity level on pregnancy rate in Holstein dairy cows using the Ovsynch protocol”

13:25-14:00

Aili Tagoma

UT/EMU

Discussion about Marie-Sklodowska Curie postdoc application

 

If you have any questions about these seminars or you would like to have some further information, please contact Hemminki Otstavel (hemminki.otstavel@ut.ee).

 

 

First presentation of a new series of scientific seminars on 16th of January 2017

 

 

We are excited to announce that the first presentation of a new series of scientific seminars was very successful. It took place on 16th of January in the seminar room on the second floor of the UT's Translational Medicine Centre (Ravila 14b, Tartu). 

 

The presentation was given by Shaghayegh Basatvat, who is a PhD student from the Alireza Fazeli's research group at the University of Sheffield. The title of her presentation was: "Investigating the Tribbles-2 modulation of innate immune system during embryo implantation using 2D and 3D cell culture models".

"Successful embryo implantation is a compulsory yet cryptic episode in reproduction. The maternal innate immune system, specifically the Toll-Like Receptors (TLRs) as the main family of pathogen recognition receptors, is involved in maintaining the immunity in the female reproductive tract. Activation of TLRs with their specific ligands, during the implantation process has a negative effect on the implantation outcome. Tribbles proteins, a family of psuedokinase proteins, modulate various signaling pathways within the cell. Tribbles-2 (Trib2) protein is modulating TLR5 signal transduction pathway. We have shown that Trib2 knockout female mice were infertile. Hence, we hypothesized that Trib2 protein is involved in regulation of female fertility. Initial investigations demonstrated that embryo implantation failure might be the main cause of infertility in the female Trib2 knockout mice. Thus, the aim of this study is to understand the role of Trib2 in embryo implantation and regulation of TLR5 signaling pathway and as a result how this protein is involved in the female fertility."


The presentations slides are available here: slides


If you have any questions or suggestions about our next Journal Club presentations, please contact: Hemminki Otstavel (hemminki.otstavel@ut.ee), +37256354033

 

43rd Annual Conference of the IETS in Austin, Texas from January 14th - 17th 2017

43rd Annual Conference of the IETS (International Embryo Transfer Society) in Austin, Texas from January 14 - 17 2017. This is the largest international society for embryo transfer in non-humans. The 43rd Annual Conference of the IETS (International Embryo Transfer Society) covered a variety of topics like gene editing, molecular mechanisms regulating male and female fertility, commercial embryo production, nutritional control of oocyte and embryo quality and embryo communications. Marilin Ivask and Sulev Kõks from EMU/UT participated in the conference. In addition to gaining new knowledge and contacts, they had the opportunity to attend the DABE (Domestic Animal Biomedical Embryology) pre-conference workshop on the use of CRISPR-Cas9 for gene editing, where leading scientists and practitioners shared their experiences working with the CRISPR-Cas technology. Marilin Ivask also met with Charles R. Long from the Texas A&M University who is a leading scientist in the field of livestock genetic engineering.

Last SEARMET Steering Committee meeting in Pärnu in November 2016

 

Last SEARMET Steering Committee meeting  took place in Pärnu, Estonia on 21-23rd of  November. Different kind of project activities and upcoming trainings were discussed. Also, further  funding opportunities and upcoming research proposals were discussed between partners and possible collaborators from Poland, Germany, UK  and Italy.

 

Conference “Developing interventions for frailty” in Vienna, Austria on November 13th - 15th 2016

On November 13 - 15 2016, Sulev Kõks from UT/EMU participated in the conference “Developing interventions for frailty” in Vienna, Austria. This conference focused on the biomarker discovery and study design problems related to the age-related diseases. Biomarker discovery requires analysis of complex biological data and machine learning. One topic was cellular senescence and regenerative decline that is fundamental for ageing and degenerative disorders. There was session about neurodegenerative disorders (Parkinson’s disease, Alzheimer’s disease). Another lecture focused on the gene and cell therapies that provide stem cell based intervention for the frailty and age-related regenerative problems. Also, the possibilities of computational physiology to enable personalised medicine were discussed. Sulev Kõks learned the biomarker study design, cell therapy and systems biology. He also participated in the round table discussions and presented the activities of Searmet project.

20th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR) and the 13th Conference of the Spanish Association for Animal Reproduction (AERA) in Lisbon, Portugal from October 27th - 29th 2016

20th Annual Conference of the European Society for Domestic Animal Reproduction (ESDAR) and the 13th Conference of the Spanish Association for Animal Reproduction (AERA) in Lisbon, Portugal from October 27 - 29 2016. Ants Kavak from EMU participated in ESDAR and AERA Conferences. He also participated in October 30th 2016 under the EU framework 7 project FECUND-PROLIFIC Final Conference that was held as ESDAR 2016 Satellite Workshop  on Topic “Innovations to improve dairy cow fertility”. During these conferences and workshop Ants met with the colleagues all over Europe, from United States of America and Australia etc. He met with lot of colleagues working in the field of animal reproduction. He had a special meeting on topic of ovum pick-up with prof Geert Opsomer, dr Jan Govaere and dr Osvaldo Bogado Pascottini. As a result of these contacts EMU was able to improve their ovum-pickup results and quality of collected oocytes.There was also a discussion with prof. Mark Growe (president of ESDAR) and dr Primoz Klinc (secretary of ESDAR) about organizing ESDAR meeting in Estonia.

SEARMET meeting in Tartu 17-19th of October 2016

 

Our last SEARMET project meeting took place in Tartu from 17- 19th of October. On 17th of October, project team had a Steering Committee meeting where different kind of project specific details and activities were discussed. In the afternoon, prof. Poul Hyttel from the University of Copenhagen conducted a workshop on topic "How do animal and human biomedicine benefit from each other?". Several PhD students, researchers and other staff members from EMU, UT and CCHT participated.

 

On 18th of October experts from UCPH provided supervision for EMU staff in the laboratory, where they had discussions about in vitro embryo production; preparations for oocyte aspiration, IVM and preparations for OPU. In the afternoon EMU's OPU-technicians Jevgeni Kurykin and Andres Reilent carried out the procedure in Rahinge Farm. After practical part OPU IVM and discussions about IVF and IVC were conducted. At the same time, prof. Poul Hyttel from UCPH and prof. Alireza Fazeli from USFD had a tour of the facilities and laboratories of the Institute of Molecular and Cell Biology in University of Tartu.

During the last day of the meeting, conclusions about the work at the laboratory and protocols on bovine IVF embryo production were discussed between the project partners.

 

Seminar for PhD students in Tartu on 12th of October

 

The main purpose of this seminar is to give an opportunity for PhD students from EMU and UT to present their research and receive recommendations and feedback for their future work. Each of the students will give a 15-minute presentation on specific topic as for example the last experiment that was done in the laboratory or an experiment that was just finished. Also the presentations on the future experimental project and design are suggested. After each presentation, there will be a discussion. In the result of these seminars the quality of the research will increase.

 

 

EPICONCEPT Conference “Epigenetics and Periconception Environment” in Giardini Naxos, Italy on September 26th-29th 2016

EPICONCEPT (Epigenetics and Periconception Environment, COST Action FA1201) Conference “Epigenetics and Periconception Environment” in Giardini Naxos, Italy on September 26.-29.09 2016. Marilin Ivask from the UT/EMU participated in this conference. At this meeting the latest results and trends in the field of epigenetics and reproductive biology were presented. For example, how to solve the epigenetic problems associated with cloning. Additionally acquainted with researchers, for example Pasqualino Loi, active in this field, who are interested in future cooperation on cloning. Also Prof. Alireza Faseli from Sheffield University participated at this meeting, with whom different topics were discussed.

Danish Society for Biochemistry and Molecular Biology meeting "CRISPR genome editing: From high-throughput screening to disease models" in Copenhagen, Denmark in September 22th - 23rd 2016

Danish Society for Biochemistry and Molecular Biology meeting "CRISPR genome editing: From high-throughput screening to disease models" in Copenhagen, Denmark in September 22 - 23 2016. Marilin Ivask from EMU/UT participated at the meeting about CRISPR-Cas genome editing, where the latest results and the ways in which this technology is applied around Europe was presented, and how to solve uprising problems or what is the most difficult task to achieve with this technology. She was also acquainted with companies that provide CRISPR-Cas services in Europe. Marilin Ivask met researches in this area, creating contacts for future work. For example, she met with Simon Lillico from Bruce Whitelaw’s group at The Roslin Institute and talked about their current work with CRISPR-Cas.

The Annual Meeting of the Scandinavian Physiological Society in Oslo, Norway from August 26th - 28th 2016

The Annual Meeting of the Scandinavian Physiological Society in Oslo, Norway from August 26 - 28 2016. Ehte Orlova and Margus Eimre from UT participated in the meeting. The Annual Meeting consisted of lectures by leading experts in fields of different subjects of physiology – Heart and skeletal muscle physiology, Mitochondrial physiology, Nervous system physiology, Vascular physiology, Renal physiology. It was possible to hear and discuss the research presentations of scientists, whose papers are published in highly ranked journals. The audience obtained better understanding regarding how the function of mitochondria is regulated in the heart and skeletal muscles, how it affects the overall function of the cardiovascular system, and how one intervenes with mitochondria and metabolism. During moderated poster sessions Margus Eimre had a poster presentation titled „Changes of Intracellular Energy Transfer Enzymes in Muscles of Mice with Deleted Wolfram in (wfs1) Gene“. Results presented on poster demonstrated drop in total activities of creatine- and adenylate kinase in m. rectus femoris of wfs1 deficient mice, but unchanged functional coupling of kinases and mitochondria in this muscle. Ehte Orlova had a poster presentation titled „Expression of Mitochondrial Proteins and Respiration in Muscles of Mice with Deleted Wolfram in (wfs1) Gene”. The poster presented results regarding expression of proteins in heart and skeletal muscles assessed by Nano-LC-MS/MS analysis. Both presentations were very well accepted. Abstracts were published in Acta Physiologica in February  2017 (p17 P-29 and p 27 P- 31) http://onlinelibrary.wiley.com/doi/10.1111/apha.12841/abstract. Annual Meeting was invaluably informative and helped to generate multiple novel ideas how to pursue the research work further especially with connection to the role of metabolic intermediates as signaling mechanisms, and novel biomarkers identified through metabolomics analyses.

The XXXIth Congress of the European Association of Veterinary Anatomists (EAVA) in Vienna, Austria from July 27th - 31st 2016

The XXXIth Congress of the European Association of Veterinary Anatomists (EAVA) in Vienna, Austria from July 27 - 31 2016. Esta Nahkur from EMU participated in the conference which was organized by the Vienna School of Veterinary Medicine. She had a presentation entitled „Bone mineral density of the osseous pelvic floor in cows – a pilot study“. During the conference Esta met with Elisabeth Persson  from Swedish University of Agricultural Sciences with whom they discussed possible future collaborations.

SEARMET meeting in Sheffield in July 2016

 

SEARMET first project meeting in UK, Sheffield took place on 17 - 23rd of July 2016. The meeting was very productive and useful. Staff people from USFD gave several interesting lectures on topics such as IP and Commercialisation at the University of Sheffield, EU grants and how to write research funding proposals. More specific reasearch presentations included topics such as "Using different implantation models in vivo and In vitro to decipher cross-talk between embryo and Mother", "Biodiversity and epigenetics; what can we learn from exotic species?", "Imaging and analysis in 5D, X,Y,Z,T,Lambda", "Characterising extracellular vesicles produced by Reproductive cells" and "Different implantation models". In the evenings our hosts from USFD had organized different entertaining events, for example hiking around the lake.

               

 

Course “Statistical Data Analysis for Genome Scale Biology” CSAMA in July 10th - 16th 2016

From July 10 - 16 2016, Sulev Kõks from EMU/UT participated in a course “Statistical Data Analysis for Genome Scale Biology”, CSAMA 2016.​ The training was about reproducible research and how to implement R Studio to improve reproducibility of research. Training took place in  Bressanone-Brixen, Italy. Training was focused on topics such as transcriptomics, genetic variations, epigenomics, proteomics and metabolomics. One session was specifically dedicated for the reproducible research and implementation of R studio. It was a one week training with different lectures and practicals. Sulev Kõks will conduct a training for EMU researchers in this topic during SEARMET Winter School in November 2017.

International Workshop on Wolfram Syndrome in Vannes, France from June 27th-28th 2016.

International Workshop on Wolfram Syndrome in Vannes, France from June 27-28 2016. Wolfram syndrome is rare syndrome that is also characterised by declined reproduction. The central problem in Wolfram syndrome is decline in regenrative potential in different tissues. During the conference researchers from Europe and the US discussed potential treatment options and drug development possibilities for the Wolfram syndrome. They discussed existing models and planned further drug development studies. Sulev Kõks presented the most recent data from the works with Wolfram syndrome mice. This mouse is very good model for drug development and translational studies. Sulev Kõks learned how to prepare the drug development projects for different funders and what are the metabolic changes related to the regenerative decline in Wolfram syndrome.

Professor Alireza Fazeli visited EMU researchers in May 2016

 

Professor Alireza Fazeli from the University of Sheffield visited Tartu from 29 - 31 of May 2016. He listened to presentations from the researchers of SEARMET Estonian partners, Estonian University of Life Sciences and University of Tartu. Eight students from EMU and UT introduced their work to Professor Fazeli. The whole aim of the visit was to help researchers with their research work and give them more support and useful advice on how to conduct their work. The expert from UK was also entertained outside of the academic environment. Professor Fazeli and project coordinator Hector Pagan attended Tartumaa Folk Dance Festival „HINGEPUU“ in Raadi park where Professor Ülle Jaakma from EMU was performing.

 Professors Alireza Fazeli and Ülle Jaakma during Tartumaa Folk Dance Festival „HINGEPUU“ in Raadi park. Image: Alireza Fazeli

 

EPICONCEPT Workshop “Cross-species Epigenetics, Gametogenesis and Embryogenesis” Velingrad, Bulgaria in May 18th - 19th 2016

EPICONCEPT (Epigenetics and Periconception Environment, COST Action FA1201) Workshop “Cross-species Epigenetics, Gametogenesis and Embryogenesis” Velingrad, Bulgaria in May 18 - 19 2016. The workshop had around 50 participants from 16 countries. The main topic was Epigenetics and Periconception Environment presenting new data on cross-species epigenetics, gametogenesis and embryogenesis. The presentations were divided within 4 main themes: 1. Disease and Welfare, 2. Immune System, 3. Stress and Nutrition and 4. Targeted Drug Delivery. Marilin Ivask from EMU/UT, Aili Tagoma and Rutt Lilleoja from EMU participated in the workshop. Marilin Ivask participated with an oral presentation titled “Pregnancy rates and blastocyst yields with different transgenic cell lines in bovine cloning” at this meeting. Aili and Rutt were able to find new contacts within researchers working in the similar field in Europe, as well as strengthen already established contacts with University of Sheffield in terms of possible future collaborations.

Medical A.R.T. Seminar “Challenges for Today: Assisted Reproduction Technologies” in Tallinn, Estonia on May 12th 2016

Medical A.R.T. Seminar “Challenges for Today: Assisted Reproduction Technologies” in Tallinn, Estonia on May 12th 2016. A multidisciplinary seminar on “Assisted Reproduction Technologies” (A.R.T.) intended to produce an open public debate on the topic. Marilin Ivask from EMU/UT and Jan Ole Bertelsen Secher from the University of Copenhagen who is an expert in experimentation with transgender animals and micro manipulation participated in the international symposium. Marilin Ivask was an invited speaker and had an oral presentation titled “Potential of transgenic animal technologies for the modern biotechnology industry”. In addition to presenting the work done at EMU/UT, she learned about very interesting A.R.T. science done in Belgium and developed new contacts.

Conference "Preclinical interventions in ageing, frailty and multimorbidity” in Madrid from April 11th - 14th 2016

Conference "Preclinical interventions in ageing, frailty and multimorbidity” in Madrid from April 11 - 14 2016. Sulev Kõks introduced recent paper "Mouse models of ageing and their relevance to disease. Kõks S, Dogan S, Tuna BG, González-Navarro H, Potter P, Vandenbroucke RE. Mech Ageing Dev. 2016 Dec;160:41-53. doi: 10.1016/j.mad.2016.10.001. Epub 2016 Oct 4. Review.” (http://www.sciencedirect.com/science/article/pii/S0047637416302147). The conference itself focused on age-related  problems, frailty and comorbidties. Frailty involves also decline in the reporoduction. The conference had two parts - one was related to preclinical models, the other for clinical conditions. Our researchers were involved in the round table were frailty in relation to reproduction and regenerative potential was discussed. Declined regeneration with ageing leads to common age related problems like osteoporosis and sarcopenia. Sulev Kõks presented his works and learned how to model frailty syndrome in mice.

SEARMET meeting in Copenhagen, Denmark in 4 - 7th of April 2016

 

During our SEARMET Denmark meeting people from EMU, UT and USFD were given a tour around the facilities at the Frederiksberg Campus at UCPH. Presentations, IVF, OPU.

The slides of the presentations are available here: slides

 

 

Annual Meeting at Experimental Biology (ASPET) in San Diego, California from April 2nd - 6th 2016.

Annual Meeting at Experimental Biology (ASPET) in San Diego, California from April 2 - 6 2016. This is the main meeting for biomedical researchers in the US. Experimental Biology is the annual meeting of six societies comprised of more than 14,000 scientists and 50 guest societies. Sulev Kõks is the member of American Physiological Society (APS) and American Society for Investigative Pathology (ASIP). EB2016 is annual meeting for both of these societies. Primary focus areas include anatomy, biochemistry and molecular biology, investigative pathology, nutrition, pharmacology, and physiology. EB 2017 is open to everyone with interest in the latest research impacting life sciences. Attendees represent scientists from academic institutions, government agencies, non-profit organizations and industry. This multidisciplinary, scientific meeting features plenary and award lectures, workshops, oral and posters presentations, on-site career services and exhibits spotlighting equipment, supplies and publications required for research labs and experimental study. Sulev Kõks from EMU/UT and Marite Ehrlich from UT participated in the meeting with poster presentations. Both researchers received new information about the physiology of reproduction, ageing and regeneration.

SEARMET kick-off meeting in Estonia in February 2016

 

SEARMET project official kick-off meeting took place in Tartu, Estonia in February 2016. During three days, our partners from the University of Copenhagen and the University of Sheffield were introduced to the people working for SEARMET project from the University of Tartu and Estonian University of Life Sciences. Experts from UCPH and USFD conducted several workshops for EMU's staff on topics such as how to develop innovative and effective methods for translating periconception research into course content and how to do conference presentations. Partners from Denmark and UK also had the tours of the facilities of EMU, UT and the National Centre for Translational and Clinical Research. For cultural exchange purposes, our guests were taken to South-Estonia for an Estonian dinner.

 

  

 

 

42nd Annual Conference of IETS in Louisville, Kentucky from January 23 - 26th 2016

42nd Annual Conference of IETS (International Embryo Technology Society) in Louisville, Kentucky from January 23 - 26 2016. The 42nd Annual Conference of the IETS focused on basic and applied topics in the overall main theme of embryo resilience in the face of biotechnology, including aspects on the effect of the environment on gamete competence and embryo development, differentiation pathways and early embryo developmental competence, impact of events between ET and pregnancy recognition on pregnancy outcome and/or early embryo mortality and long term consequences of early developmental events. Marilin Ivask from EMU/UT and Elina Mark from EMU participated in the conference. New research results in the field of producing in vitro bovine embryos were introduced. Moreover, the conference provided several new contacts and potential collaborating partners for researchers. Marilin Ivask participated as a co-author of the poster titled "Improved post-thaw survival of bovine embryos produced in serum-free in vitro production system" (http://agris.fao.org/agris-search/search.do?recordID=US201600048186).